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“Every great advance in science has issued from a new audacity of imagination.”
Stem cells have been a buzzworthy topic in the medical field for many years, and their popularity is rising.
The attention these powerful cells generate is well-deserved, as they have unique abilities, unlike those of any other cells. We're now offering stem cell therapies as part of our commitment to staying at the forefront of emerging practices and deliver the highest quality of care to our patients.
Stem cells are the cells from which other cells with specialized functions are created. Whether in the body or in a laboratory, these cells are able to divide to form more cells, called daughter cells, under the right conditions.
They have the capacity to duplicate indefinitely and can change into various cell types, from muscle cells to brain cells. Daughter cells also have the ability to become new stem cells, which is referred to as self-renewal, or become specialized cells, known as differentiation.
Stem cells are the only cells in the body with the ability to differentiate into blood, brain, heart muscle, or bone cells.
These powerful capabilities hold enormous potential in therapeutic applications. From helping to improve quality of life in individuals with autoimmune diseases to supporting general wellbeing and delivering anti-aging effects, there are many applicable therapies for which stem cells have been shown to be beneficial.
Yet, the quality and source of the stem cells is tremendously important in achieving optimal outcomes.
While adults have stem cells which can be extracted from bone marrow and adipose (fat) tissue, these cells age with the rest of the body. The younger stem cells are, the more powerful they may be.
For this reason, mesenchymal stem cells isolated from umbilical cord tissue are often used. These cells are highly expandable but retain the ability to differentiate. They also have immunomodulatory and anti-inflammatory properties, making them a promising therapeutic option for a broad range of conditions.
Stem cells can either be derived from the patient (known as autologous stem cells) or provided from a donor (called allogeneic stem cells).
Autologous stem cells minimize the possibility of rejection, but they require a surgical procedure for extraction and are as old as the age of the patient at the time of the extraction. For this reason, they are unlikely to be as effective as allogeneic stem cells and may carry inherent issues.
Allogeneic stem cells are usually young cells and require no surgical intervention.
Cenegenics® screens donors to ensure that the stem cells are verified, quality products. Potential donors are extensively screened for medical, social, family health, lifestyle, and recent travel considerations.
Blood is also tested by a certified lab to look for conditions such as HIV and hepatitis. Stem cells are stored in a regulated cleanroom environment and overseen by staff with extensive training. There are protocols for every step with strict quality assurance and quality control standards in place.
Once it has been determined that a patient is an ideal candidate for stem cell therapy, they can enter into the Cenegenics® stem cell program overseen by a trained and experienced physician. The patient and physician will work together to create an appropriate program and course of treatment.
In most cases, patients receive 100 million mesenchymal stem cells administered through a simple IV infusion. Patients are made to feel comfortable in a luxurious suite while the infusion is administered, and the entire process is simple and painless.
Stem cells work by distinguishing signals sent out by sick or destressed cells that tell the body which changes are needed. These signals tell stem cells where they need to go and what is necessary for repairs to take place.
They also work by releasing factors that help control the immune system (immune modulation) and increase blood flow (angiogenesis), thereby aiding in the healing and repair of your entire system. For this reason, stem cell therapy is well-suited to address a number of challenging medical issues which may not always respond well to traditional therapies.
The applications for stem cell therapy are constantly evolving, as researchers are consistently finding new conditions that stem cells can benefit. As of now, some of the most common applicable therapies include:
Osteoarthritis affects an estimated 30 million individuals across the U.S., especially those over the age of 60.
In patients with this condition, joints become damaged as a result of typical wear and tear. The joints have a poor capacity for healing and repair, and cartilage regeneration is minimal or incorrectly repaired.
In studies, individuals who received stem cell therapy for osteoarthritis experienced a significant reduction in pain, and an improvement in self-reported quality of life. Patients also tolerated the doses well without any serious adverse effects.
It’s estimated that 50 million Americans have an autoimmune disease.3 In these conditions, an immune response damages healthy cells. In patients with rheumatoid arthritis (RA), for instance, the immune system attacks healthy joints, causing lasting damage. Because stem cells have an immune modulation response and can differentiate into bone cells, it’s suspected that stem cell therapy may soon become a go-to treatment for individuals with RA and other autoimmune conditions.
Aging is associated with a wide range of disorders. To combat these issues, the body must be able to control the acute inflammatory response.
When inflammatory markers are elevated, chronic diseases commonly seen throughout aging, including cardiovascular disease, may ensue. While aging is a natural process, stem cells may act as immune system modulators to decrease the pro-inflammatory response and increase the anti-inflammatory response, thereby helping to slow or deter many of the detrimental factors associated with aging.
A key process that declines with age is the body's production of stem cells. Mesenchymal stem cells, in particular, work by stimulating the body itself to regenerate. They secrete a range of cellular products, molecules, and exosomes that act in different ways to stimulate the body's own healing process.
In addition to the applications listed above, stem cell therapy has also been used in neurodegenerative conditions, as well as conditions of the heart and lungs.
The benefits of stem cell therapy span far and wide. For one, the treatment can be used as a supplemental or alternative therapy to other approaches. And, in studies, it has been shown to produce little to no adverse events.
Mesenchymal stem cell therapies have been used in more than 800 registered clinical studies across the globe with more than 3,000 citations to publications, positioning them among the most intensely pursued and promising cellular therapies.
Tens of thousands of patients have been treated worldwide with stem cells from donors with few to no adverse effects. In the 3% of patients who have reported adverse effects, the most common side effects were chills, nausea, and body aches, all of which are seen only immediately after treatment and resolve quickly.
Of course, while stem cell therapy is widely considered safe, infusions must be monitored just as any modern transfusion of cell transplantation would. There are many steps involved with assuring safety, which is why it’s critical to work with only the most trusted providers when seeking this treatment.
In addition to its overall safety and minimal risk of side effects, stem cell therapy is also becoming more widely sought-after due to its ability to improve quality of life. These cells address immune imbalances and inflammation and stimulate regeneration in ways other cells cannot.
They can help patients who have not experienced ideal outcomes from traditional therapies achieve an enhanced quality of life. And, even for healthy individuals, they may serve as a powerful preventive measure to help control the effects of aging. The healthier and more intact your stem cell population, the more likely you are to maintain a healthy, youthful lifestyle.
If you believe you could be a good candidate for stem cell therapy, don’t hesitate to contact your Cenegenics® team. Currently, the treatment is only available at the Cenegenics® Mexico locations, conveniently located in Mexico City and Los Cabos, Baja California. As with all Cenegenics® program, stem cell therapy is completely personalized, so patients should schedule their treatment in advance. Your Cenegenics® Mexico-International Health Concierge will be happy to make all necessary arrangements for your stem cell therapy, including extensive laboratory studies, a two-night hotel stay, and airport transfers. For inquiries, please reach out to [email protected] and cc [email protected].